Abstract
Rationale, aims and objectives: Little is known about hesitancy to receive the
COVID-19 vaccines. The objectives of this study were (1) to assess the perceptions
of healthcare workers (HCWs) and the general population regarding the COVID-19
vaccines, (2) to evaluate factors influencing the acceptance of vaccination using the health belief model (HBM), and (3) to qualitatively explore...
ABSTRACT
Apixaban (APX) is a potent oral anticoagulant drug that directly inhibit coagulation factor Xa for prevention of venous thromboembolism (VTE) following total hip or knee replacement surgery. Orally APX has poor water solubility (0.028 mg/mL) and relative low bioavailability (50%). Transdermal APX delivery was utilized as a convenient alternative route to control oral limitations....
Proposal of A national, multicenter study on the psychological effects and physical symptoms experienced by healthcare staff during the COVID-19 outbreak pandemic in Iraq.
Abstract
Background: The novel coronavirus 2 (SARS‐CoV‐2) pandemic poses a serious threat to public health and local economies around the globe. It is a pulmonary disease, but it also leads to cardiac, hematologic, and renal complications. Hematologic complications are represented by Thromboembolic events which occur in patients with COVID-19. Anticoagulants are used for COVID-19 infected...
Breast cancer is the most common cancer among women over the world. To reducing reoccurrence and mortality rates, adjuvant hormonal therapy (AHT) is used for a long period. The major barrier to the effectiveness of the treatment is adherence. Adherence to medicines among patients is challenging. Patient beliefs in medications can be strongly or negatively correlated to adherence. Objectives:...
This study was intended to assess the situation of essential medicines for the implementation of the sexual and reproductive health and rights (SRHR) guidelines in Iraq to provide a clear picture of the availability of these medicines and identifies gaps to be filled. The medicines were grouped into categories and subcategories and the assessment was begun after collecting information from the...
Objective. To evaluate the knowledge and views of pharmacists and pharmacists in sports and to investigate curriculum needs for sports pharmacy undergraduates
Methods. A web-based cross-sectional survey of pharmacy students was carried out from 2nd of Feb to 5th of March 2021 at the University of Mosul, College of Pharmacy. Survey Heart programs have been used to collect data and process...
Purpose: In this work a rituximab follow-on biologic, Zytux, was tested for its biosimilarity to the reference originator product, MabThera.
Methods: The test involved an analytical assessment exercise done head-to-head on samples of Zytux and MabThera withdrawn randomly from the Iraqi governmental hospitals. This analytical assessment encompassed methods for comparing the quality aspects of...
The impairment of cardiovascular autonomic control among the underdiagnosed complication
of diabetes mellitus (DM) with a high prevalence rate of up to 60% in type 2 DM (T2DM). Cardiac
autonomic neuropathy (CAN) is an independent risk factor for cardiovascular mortality, arrhythmia,
silent ischemia, any major cardiovascular event, and heart failure. We aimed to evaluate
cardiovascular...
Does the Life Style of Iraqi Healthcare Providers ( physicians, pharmacists and dentists) and medical group Students Protect from Hypovitaminosis D3?
Hanaa Kadhem, BS Pharm, Assist Prof. Zinah Mudhafar.
Clinical Pharmacy Department, College of Pharmacy, University of Baghdad, Baghdad, Iraq.
The research is abstracted from the Higher Diploma thesis.
Hanaa Kadhim Fadhil, BS Pharm,...
Purpose: To evaluate knowledge, practice and attitude of community pharmacists in Basra regarding modified release dosage forms which are widely used for many therapeutic purposes in pharmacy practice.
Methods: The current study was conducted among certified pharmacists in Basra governorate- south of Iraq. Data collection was carried out by a questionnaire.
Results: A total number of 175...
Abstract:
Backgrounds: The prevalence of unused medications domestically by households has been dramatically increased in recent years; this has resulted in a robust waste of medicines. The public, healthcare providers and governments are all accused of promoting medications wastage in different ways and thus, they need to be targeted to solve this problem. The aims of this study were...
AbstractPsoriasis is a long-lasting autoimmune disease that is characterized by swollen skin patches. Normally, these skin patches are dark, swollen, itchy and scaly. The single application of the innate Toll-like receptor7/8 ligand Imiquimod (IMQ) in mice easily induces a dermatitis that closely resemble human psoriasis, critically dependent on the axis of interleukin-23/interleukin-17. The...
The present investigation aimed to formulate a liquid self-microemulsifying drug delivery system (SMEDDS) of tacrolimus to enhance its oral bioavailability by improving its dispersibility and dissolution rate. Four liquid SMEDDS were prepared using maisine CC as oil phase, labrasol ALF as surfactant and transcutol HP as co-surfactant based on the solubility studies of tacrolimus in these...
Background
For many years it was argued that there may be gender based differences in adverse drug reactions. This assumption was based on the presence of gender related pharmacokinetics, pharmacodynamics, hormonal and behavior variations. The dissimilarities were not clearly identified since the females are underrepresented in the clinical trials. Individual case safety reports database...
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
CONCLUSION
ACKNOWLEDGMENT
REFERENCES
Abstract
Background: Breast cancer is a threatening disease for women's health globally. CA 15-3 is a tumor marker used in conjugation with other tests and procedures in monitoring treatment response, disease recurrence, and cancer metastasis. Many biological substances have been recognized to play a beneficial role in reducing oxidative stress and enhancing antioxidant states for patients...
New derivatives (4A-4D) were designed and synthesized from, picolinic acid (PA). The newly synthesized compounds were confirmed by ATR-FTIR, 1HNMRS, 13CNMR and CHNS analysis. The molecular docking methodology of (4A-4D) against EGFR kinase revealed that certain compounds occupied the vital site of EGFR kinase pocket and with a good fit. By employing the MTT assay, it was found that. compound...
ABSTRACT
The rheological behavior among factors that are present in Stokes law can be used to control the stability of the colloidal dispersion system. The felodipine lipid polymer hybrid nanocarriers (LPHNs) is an interesting colloidal dispersion system that is used for rheological characteristic analysis. The LPHNs compose of polymeric components and lipids. This research aims to prepare...
ABSTRACT
Background: cell lines derived from cancer cells are frequently used in research, including use as a model to understand cancer and to identify potential new treatments. The aim of this article has been prepared to evaluate the anticancer effect of Rumex Acetosella that has been studied for their anticancer activity on esophagus and breast cancer cell line. Method: AMJ13 (new breast...
The effect of Anabasis articulata stems extract on lowering intraocular pressure in the glaucoma rat model
Waleed K. Abdulsahib
Pharmacology and Toxicology Department, College of Pharmacy, Al- Farahidi University, Baghdad, Iraq.
Baghdad, Iraq.
Address correspondence: Waleed K. Abdulsahib
Pharmacology and toxicology department, College of pharmacy,
Al- Farahidi University, Baghdad, Iraq....
Abstract
Objective: the idea of this study to improve transdermal permeability of Methotrexate using eucalyptus oil, olive oil and peppermint oil as enhancers.
Method: eucalyptus oil (2% and 4%), peppermint oil (2% and 4%) and olive oil (2% and 4%) all used as natural enhancers to develop transdermal permeability of Methotrexate via gel formulation. The gel was subjected to many...
Experimental evidence suggests that safranal, an organic compound, isolated from saffron (Crocus sativus) had anti-inflammatory and antioxidant effects. In the present study, we investigated the protective effect of safranal on the lipopolysaccharide LPS induced acute lung injury ALI model. Sixty albino BALB/c male (20-30g) mice were divided into five groups: control group (vehicle...
Renal system is vital for total body homeostasis because the kidney plays a
principle role in the excretion of metabolic waste products and in the
regulation of extracellular fluid volume, electrolyte composition, and acidbase balance. Amikacin induced renal toxicity including a variety of
pathophysiological effects i.e. inflammation, specific transporters inhibition
,induction of...
Abstract
Autoimmune hepatitis is an inflammatory disease and its incidence has been increasing. The features of hepatitis are the release of inflammatory cytokines, the elevation of AST and ALT, and hepatocyte apoptosis and necrosis. Concanavalin A considered as essential model represents the acute immune-mediated liver damage in rodents. Thymoquinone is well known herbal compound that exert...
Abstract
Objectives: The study objectives were to 1) explore the real-world experience of hospital pharmacists with the differences in effectiveness safety, and interchangeability between biosimilar medicines and their reference biological counterparts, 2) reveal pharmacist recommendations to enhance the safety of biopharmaceutical medicines in public hospitals.
Methods: The study has a...
