(Current Challenges and Updates in Pharmacy Education and Research)مؤتمر

25 Aug 2021, 03:05 → 26 Aug 2021, 20:00 Asia/Baghdad

كلية الصيدلة

College of Pharmacy – University of Baghdad

Held 9TH Scientific Conference on

(Current Challenges and Updates in Pharmacy Education and Research)

in August 25-26, 2021 (Virtual)

Manuscript Submission: 

- The authors should determine the track of his manuscript (See conference tracks).

- The submitted manuscripts must not be previously published.

- All manuscripts are presented to the scientific committee of the conference to determine the appropriateness of the research to participate.

- All submitted papers are sent to three reviewers to undergo a double-blind peer review process. At least two responses should be received for the decision to be taken.

- The accepted manuscripts are presented either during conference session or as poster.

- Accepted manuscript will be published in the Iraqi Journal of Pharmaceutical Sciences (IJPS) (Scopus indexed)

- The Manuscript's abstracts are sent within the conference submission link, and the full text sent via a conference email.

Guidelines for Author: click here https://bijps.uobaghdad.edu.iq/index.php/bijps/Guidelines

---

The conference proceedings will be held on the Zoom platform, according to the entry information below:

شهادات المشاركة مؤتمر كلية الصيدلة جامعة بغداد 2021.pdf

Wednesday, 25 August

09:00 → 09:15 Exploring the acceptance of COVID-19 vaccine among healthcare workers and general population using health belief model

Abstract
Rationale, aims and objectives: Little is known about hesitancy to receive the
COVID-19 vaccines. The objectives of this study were (1) to assess the perceptions
of healthcare workers (HCWs) and the general population regarding the COVID-19
vaccines, (2) to evaluate factors influencing the acceptance of vaccination using the health belief model (HBM), and (3) to qualitatively explore the suggested intervention strategies to promote the vaccination.
Methods: This was a cross-sectional study based on electronic survey data that was
collected in Iraq during December first-19th, 2020. The electronic survey was
designed using Qualtrics. HBM was followed to develop the survey items. A regression
analysis was used to identify factors influencing people accepting vaccination.
Thematic analysis for participant comments to an open-ended question.
Results: A total of 1680 completed surveys were received. The mean age of 31.2
± 9.9 years, 53.0% were female and 47.0% were male. The largest group was HCWs
(45.7%), followed by the general population (37.5%) and health college students (16.8%). Our findings expressed some hesitancy to receive the COVID-19 vaccine with the acceptance
rate of 61.7%. The HCWs perceived significantly higher susceptibility and severity of the
COVID-19 infection compared to the general population. The HCWs were significantly
more likely than the general population to receive COVID-19 vaccine. Concerns with
proper storage were the biggest barrier to vaccine receipt. The regression analysis indicated
eight factors that were significantly associated with the willingness to receive the COVID-19 vaccine: Preventive measures, perceived benefit, perceived barriers, cue to action, subjective
norm, supportive of vaccination in general, and having received a flu vaccine before.
Conclusions: An awareness campaign can focus on enhancing the vaccine perceived
benefit, debunking misconceptions, and increasing the disease's perceived severity.
Additionally, public health leaders need to minimize the perceived barriers by
providing the vaccines and appeasing people's concerns about their storage, effectiveness, and adverse events.

Speaker: Dr Ali Azeez Al-Jumaili (University of Baghdad College of Pharmacy)

Thursday, 26 August

09:00 → 09:15 Apixaban Ultrafine O/W Nano Emulsion Transdermal Drug Delivery System: Formulation, In Vitro and Ex Vivo Characterization

ABSTRACT
Apixaban (APX) is a potent oral anticoagulant drug that directly inhibit coagulation factor Xa for prevention of venous thromboembolism (VTE) following total hip or knee replacement surgery. Orally APX has poor water solubility (0.028 mg/mL) and relative low bioavailability (50%). Transdermal APX delivery was utilized as a convenient alternative route to control oral limitations. This study designed to formulate ultrafine APX o/w nanoemulsion with self-permeation enhancing properties through skin barrier utilizing the ultrafine (less than 50 nm) nanosized droplets as well as nanoemulsion components themselves to act as a permeation enhancer. Solubility study result in selecting triacetin oil, triton-x-100 and carbitol as oil phase, surfactant and cosurfactant respectively, while pseudoternary phase diagram construct nanoemulsion area for choosing formulations.
Twenty-one o/w nanoemulsions prepared and characterized for droplet size, pH values, percent transmittance, electroconductivity, APX content, in vitro APX release, and ex vivo permeation through Albino Wistar rat abdominal skin to simulate human skin. Among formulations, ten preparations demonstrate ultrafine APX o/w nanoemulsions with high percent transmittance and electroconductivity, pH values appropriate for skin application, ultrafine droplet sizes (less than 50 nm) and accepted APX content. In vitro release studies reveal significant (p ≤ 0.05) increase in APX dispersibility and diffusion through dialysis membrane. Ex vivo APX permeation through rat abdominal skin was significantly (p ≤ 0.05) increased in comparison with pure drug as assured by significant (p ≤ 0.05) enhancement in permeation parameters Jss, KP and ER with shorter Tlag, which could be attributed to permeation enhancing properties of nanoemulsion formulation itself.

Key words: Apixaban (APX); Ultrafine o/w nanoemulsion; transdermal drug delivery.

Speaker: Dr. Mustafa Aljazairy (College of Pharmacy / Al-Bayan University)