(Current Challenges and Updates in Pharmacy Education and Research)

Prevalence of multidrug resistance bacteria and its association with patients’ predictive factors

Not scheduled

20m

كلية الصيدلة

Recorded poster Conference Trak Two

Speaker

Mrs Zhraa Fakhreldain (Kufa university/college of pharmacy)

Description

Background
Antimicrobial resistance(AMR) is a potentially disastrous problem that is mounting Globally. The surveillance studies are vital to contain the spread of AMR by creating evidence for national and global management and actions. the incidence of multidrug resistance bacteria (MDR) has been studied to a lesser extent in Iraq. Therefore, our study aimed to collect data evaluating the prevalence and antibiotic susceptibility patterns of MDR and explore the patient’s predictive factors associated with it.
Methods
The study was an observational cross-sectional study conducted in a microbiology lab in AL-Zahraa teaching hospital and ALSadar medical city, in Najaf Province, Iraq. The participants included both inpatient and outpatients of both genders present with different kinds of infections and requested for culture and sensitivity of the organisms isolated from different sources. The total sample size was 475 patients out of them 304 patients had a positive growth media. The data was collected from a laboratory test report that was designed to include the results of antibiotic susceptibility patterns from the culture and sensitivity test). Our study was registered at Clinical Trials.gov with the registration number (NCT05100407).
Results
The study showed a very high prevalence of MDR (88%) and the prevalence of XDR reached(23%). Whereas PDR prevalence was 2%. Specifically, MRSA was detected in 73% of the total patients infected with staph. The prevalence of ESBLs reached 56% among the patients infected with Enterobacteria. Regarding carbapenem resistance (CR) was recorded in 25% of the patients infected with different kinds of bacteria. Only education level was significantly associated with the prevalence of MDR. Patients with (college /post-graduate) education were associated with a low incidence of MDR.

Conclusion
A very high prevalence of multidrug resistance bacteria was noted in patients with a bacterial infection. Among all patients’ characters, only higher education was associated with lower incidence.