Abstract
Zavegepant-loaded spanlastics were prepared by the ethanol injection method for intranasal nose-to-brain delivery. Preliminary results showed nanosized vesicles with good PDI and satisfactory entrapment efficiency. The optimized formulation will be further incorporated into a thermoresponsive in-situ gel and evaluated for nasal permeation and brain-targeting potential.
Primary authors
Mr
Ali jawad
(al-nahrain university)
Prof.
Mowafaq M.Ghareeb
(university of baghdad)
