Hypertension is a chronic medical condition that wide spread among the elderly individuals. Hypertension has different side impacts on the oral hygiene like periodontitis and dry mouth. Hypertension with and without smoking caused considerably significant effects on the cytomorphological stability and regular changes of cells compared to control group. Exfoliative cytology can be defined as the clinical technique which can be used to determine the morphological changes in cells that have been scraped or pulled from the epithelial surface of different organs.