Epigenetics plays a significant role in male infertility by influencing gene expression without altering the DNA sequence itself. Factors such as environmental exposures, lifestyle choices, and aging can affect epigenetic marks, potentially leading to sperm abnormalities and infertility. Epigenetic modifications can impact sperm quality, including sperm motility, morphology, and DNA integrity, all of which are crucial for fertility. Understanding the epigenetic mechanisms underlying male infertility is essential for developing targeted therapies and interventions to improve reproductive outcomes.