Long-term acrylic soft denture lining materials have many advantages in prosthetic dentistry, but the nature of these materials makes them subject to different problems. One of these widely spread problems was candida albicans. Because of the difficulty in killing fungal cells and the deep penetration of fungi inside the soft denture lining material, researchers tried to find other ways to treat this problem. They depended on nanoparticles as a means of boosting the soft denture liner material's resistance to fungi, as well as its mechanical characteristics.