Prosthetic devices have frequently been employed to repair inherited or acquired abnormalities caused by cancer or trauma. Patients and prosthodontists accept silicone elastomers, but more developments are needed to improve their performance. A stronger material was created as a result of research to create a new generation of polymers with nanofiller added to the polymer matrix. This material combines the polymer's flexibility and the nanofiller's strength. The study aims to evaluate the effects of magnesium oxide nano powder addition on some properties of VST-50 maxillofacial silicone.