Gypsum and its products have been used for centuries in various fields. In dentistry, it was mainly used to make casts. These stone models are obtained from the impressions that are susceptible to contamination and can generate a contaminated gypsum cast, leading to cross-contamination between the dental personnel and the patient. The purpose of this study was to evaluate the effect of hypochlorous acid (60 ppm and 100 ppm) on some mechanical and physical properties of type III dental stone, including ultimate compressive strength, initial setting time, linear setting expansion, reproduction of details and compatibility with the impression materials.