Introduction: Tooth development, or odontogenesis, is the complex process by which teeth form from embryonic cells, grow, and erupt into the mouth. It may be affected by many factors and materials that may accelerate or slow the process and may improve or defect the tooth.
Angiopoietin 1 protein is one of these factors that cause angiogenesis to supply the tooth with more nutrients and oxygen and protects blood vessels by decreasing plasma leakage, blocking vascular inflammation, and protecting against endothelial death.
Aim of the study: Evaluation of the effect of Angiopoietin 1 protein on tooth development by measuring the enamel and dentin thickness as well as the pulp tissue cell in rat by histological, histomorphometric, and immunohistochemical studies.
