Periodontitis is an inflammatory condition brought on by an infection, and biofilms play a significant part in this disease. Dental plaque buildup at the gingival edge results in an inflammatory reaction that can modify the microbial and severely affect the periodontium of sensitive people. The main immune cells that protect against dangerous bacteria in saliva are neutrophils. However, they are also known to cause tissue deterioration in inflammatory illnesses. Antimicrobial peptides defend the host from various pathogens, such as bacteria, viruses, yeast and fungus. They also have immunomodulatory qualities that assist in controlling inflammatory reactions .